rosuvastatin

Details

Instance of

type of chemical entity

Subclass of

statin, carboxylic acid

Has parts

nitrogen, oxygen, carbon

active ingredient in

Crestor

canonical SMILES

CC(C)C1=NC(=NC(=C1C=CC(CC(CC(=O)O)O)O)C2=CC=C(C=C2)F)N(C)S(=O)(=O)C

chemical formula

C₂₂H₂₈FN₃O₆S

defined daily dose

10

different from

rosuvastatin calcium

has use

medication

isomeric SMILES

CC(C)C1=NC(=NC(=C1/C=C/[C@H](C[C@H](CC(=O)O)O)O)C2=CC=C(C=C2)F)N(C)S(=O)(=O)C

LiverTox likelihood score

LiverTox toxicity likelihood category B

mass

481.168285

medical condition treated

lipedema, heart disease, arteriosclerosis, rare dyslipidemia, atherosclerosis, familial hypercholesterolemia, lipid metabolism disorder

physically interacts with

3-hydroxy-3-methylglutaryl-CoA reductase

pregnancy category

Australian pregnancy category D, US pregnancy category X

significant drug interaction

(S)-(−)-colchicine, fenofibrate, ciprofibrate, gemfibrozil, (2R)-daptomycin, bezafibrate, (S)-(−)-colchicine, fenofibrate, saquinavir, saquinavir, ciprofibrate, ritonavir

stereoisomer of

(3R,5S)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-propan-2-yl-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoic acid, (E,3R,5R)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-propan-2-ylpyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid

subject has role

statin

World Health Organisation international non-proprietary name

rosuvastatin

Connected on Wikidata