phenytoin

Details

Instance of

type of chemical entity

Subclass of

chemical compound

active ingredient in

Dilantin, Phenytek

canonical SMILES

C1=CC=C(C=C1)C2(C(=O)NC(=O)N2)C3=CC=CC=C3

chemical formula

C₁₅H₁₂N₂O₂

has use

medication

mass

252.089878

medical condition treated

tonic–clonic seizure, epidermolysis bullosa, temporal lobe epilepsy, epilepsy

melting point

296

physically interacts with

Sodium voltage-gated channel alpha subunit 2

pregnancy category

Australian pregnancy category D, US pregnancy category D

significant drug interaction

disulfiram, vincristine, amiodarone, bortezomib, paclitaxel, cisplatin, metronidazole, isoniazid, vinblastine, L-thyroxine, bazedoxifene, diltiazem

subject has role

anticonvulsant agent, voltage-gated sodium channel blockers, cytochrome P-450 CYP1A2 inducers, developmental toxicant, carcinogen, WHO essential medicine

World Health Organisation international non-proprietary name

phenytoin

Authority files