Sodium voltage-gated channel alpha subunit 2

Details

Instance of

protein

Part of

Voltage gated sodium channel, alpha subunit, Voltage-dependent channel domain superfamily, Voltage gated sodium channel, Sodium ion transport-associated domain, protein family, Ion transport domain, protein family, Voltage-gated Na+ ion channel, cytoplasmic domain, protein family, IQ motif, EF-hand binding site, protein family

Has parts

Voltage-gated Na+ ion channel, cytoplasmic domain, Ion transport domain, IQ motif, EF-hand binding site, Sodium ion transport-associated

biological process

membrane depolarization during action potential, sodium ion transport, regulation of ion transmembrane transport, ion transport, transmembrane transport, myelination, neuronal action potential, sodium ion transmembrane transport, nervous system development, intrinsic apoptotic signaling pathway in response to osmotic stress, neuron apoptotic process, sodium ion transmembrane transport

cell component

voltage-gated sodium channel complex, integral component of membrane, membrane, intrinsic component of plasma membrane, sodium channel complex, plasma membrane, node of Ranvier, integral component of plasma membrane, intracellular anatomical structure, intercalated disc, T-tubule, axon

encoded by

SCN2A

found in taxon

Homo sapiens

molecular function

sodium channel activity, voltage-gated ion channel activity, ion channel activity, voltage-gated sodium channel activity, voltage-gated sodium channel activity

physically interacts with

phenytoin, mephenytoin, indecainide, oxybuprocaine, oxcarbazepine, Irampanel, dichlorobenzyl alcohol, priralfinamide, Evenamide, lidocaine, zonisamide, topiramate