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cabozantinib — MetaHistoryBook
cabozantinib
chemical compound
Wikipedia ↗
Images on Commons ↗
Wikidata (Q795057) ↗
Details
Instance of
type of chemical entity
Subclass of
chemical compound
active ingredient in
Cometriq
,
Cabometyx
canonical SMILES
COC1=CC2=C(C=CN=C2C=C1OC)OC3=CC=C(C=C3)NC(=O)C4(CC4)C(=O)NC5=CC=C(C=C5)F
chemical formula
C₂₈H₂₄FN₃O₅
has use
medication
LiverTox likelihood score
LiverTox toxicity likelihood category E*
mass
501.169999
medical condition treated
kidney cancer
,
thyroid medullary carcinoma
,
renal cell carcinoma
,
renal pelvis carcinoma
physically interacts with
kinase insert domain receptor
,
MET proto-oncogene, receptor tyrosine kinase
pregnancy category
US pregnancy category D
significant drug interaction
voriconazole
,
clarithromycin
,
idelalisib
subject has role
protein kinase inhibitors
,
active ingredient
Connected on Wikidata
Subject of
Cabozantinib in Patients With Hepatocellular Carcinoma (ACTION)
Trial of Cabozantinib Plus Atezolizumab in Advanced and Progressive Neoplasms of the Endocrine System. The CABATEN Study
Cabozantinib in the Elderly With Metastatic Renal Cell Carcinoma
A Study to Evaluate the Safety, Tolerability and Efficacy of Cabozantinib in Patients With Hepatocellular Carcinoma and Impaired Liver Function
Cabozantinib Combined With Ipilimumab/Nivolumab and TACE in Patients With Hepatocellular Carcinoma
Nothing in the MetaHistoryBook collection references this item yet.