loxapine

chemical compound

Details

Instance of: type of chemical entity
Subclass of: dibenzoxazepine
active ingredient in: Adasuve
canonical SMILES: CN1CCN(CC1)C2=NC3=CC=CC=C3OC4=C2C=C(C=C4)Cl
chemical formula: C₁₈H₁₈ClN₃O
has use: medication
legal status (medicine): boxed warning
LiverTox likelihood score: LiverTox toxicity likelihood category D
mass: 327.114
medical condition treated: schizophreniform disorder
physically interacts with: 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2C, 5-hydroxytryptamine receptor 6, Dopamine receptor D2, Dopamine receptor D3, Dopamine receptor D4, Histamine receptor H1, Potassium sodium-activated channel subfamily T member 1
pregnancy category: US pregnancy category C
significant drug interaction: trimipramine, amitriptyline, (RS)-baclofen, (E/Z)-doxepin, droperidol, pimozide, fluphenazine, aripiprazole, haloperidol, quetiapine, imipramine, olanzapine
subject has role: dopamine antagonist, serotonin antagonist, antipsychotics

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