digoxin

Details

Instance of

type of chemical entity

Subclass of

cardiac glycoside, cardanolides

active ingredient in

Lanoxin, Digox, Digitek

associated hazard

digoxin toxicity

canonical SMILES

CC1C(C(CC(O1)OC2C(OC(CC2O)OC3C(OC(CC3O)OC4CCC5(C(C4)CCC6C5CC(C7(C6(CCC7C8=CC(=O)OC8)O)C)O)C)C)C)O)O

chemical formula

C₄₁H₆₄O₁₄

defined daily dose

0.25, 0.25

found in taxon

Digitalis lanata, Digitalis obscura, Digitalis parviflora, Digitalis viridiflora

has use

medication

isomeric SMILES

C[C@@H]1[C@H]([C@H](C[C@@H](O1)O[C@@H]2[C@H](O[C@H](C[C@@H]2O)O[C@@H]3[C@H](O[C@H](C[C@@H]3O)O[C@H]4CC[C@]5([C@@H](C4)CC[C@@H]6[C@@H]5C[C@H]([C@]7([C@@]6(CC[C@@H]7C8=CC(=O)OC8)O)C)O)C)C)C)O)O

mass

780.43

medical condition treated

atrial fibrillation, congestive heart failure, supraventricular tachycardia, heart arrhythmia

physically interacts with

ATPase Na+/K+ transporting subunit alpha 1

pregnancy category

Australian pregnancy category A, US pregnancy category C

significant drug interaction

(RS)-metoprolol, nadolol, atenolol, nebivolol, acebutolol, betaxolol, bisoprolol, pindolol, propranolol, labetalol, celiprolol, esmolol

subject has role

enzyme inhibitor, antiarrhythmic agent, cardiotonic, WHO essential medicine

World Health Organisation international non-proprietary name

digoxin

Authority files