ATPase Na+/K+ transporting subunit alpha 1

Details

Instance of

protein

Part of

HAD-like superfamily, P-type ATPase, cytoplasmic domain N, HAD superfamily, P-type ATPase, A domain superfamily, P-type ATPase subfamily IIC, subunit alpha, P-type ATPase, transmembrane domain superfamily, Na+/K+-ATPase, Cation-transporting P-type ATPase, C-terminal domain, protein family, Cation-transporting P-type ATPase, N-terminal domain, protein family

Has parts

Cation-transporting P-type ATPase, C-terminal, Cation-transporting P-type ATPase, N-terminal, P-type ATPase, phosphorylation site

biological process

cellular response to steroid hormone stimulus, regulation of cardiac conduction, membrane hyperpolarization, regulation of sodium ion transport, regulation of the force of heart contraction, negative regulation of heart contraction, sodium ion transport, cellular sodium ion homeostasis, sodium ion export across plasma membrane, cell communication by electrical coupling involved in cardiac conduction, response to glycoside, ion transport

cell component

integral component of membrane, extracellular vesicle, endosome, Golgi apparatus, membrane, intercalated disc, T-tubule, melanosome, myelin sheath, plasma membrane, sodium:potassium-exchanging ATPase complex, basolateral plasma membrane

EC enzyme number

7.2.2.13

encoded by

ATP1A1

found in taxon

Homo sapiens

molecular function

steroid hormone binding, nucleotide binding, chaperone binding, protein domain specific binding, phosphatase activity, ADP binding, potassium ion binding, sodium ion binding, P-type sodium:potassium-exchanging transporter activity, metal ion binding, phosphatidylinositol 3-kinase binding, protein binding

physically interacts with

deslanoside, digitoxin, digoxin