irinotecan

Details

Instance of

type of chemical entity

Subclass of

Irinotecan

active ingredient in

Camptosar

canonical SMILES

CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)C5(CC)O)OC(=O)N6CCC(CC6)N7CCCCC7

chemical formula

C₃₃H₃₈N₄O₆

found in taxon

Taiwanofungus camphoratus, liquorice

has use

medication

isomeric SMILES

CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)[C@@]5(CC)O)OC(=O)N6CCC(CC6)N7CCCCC7

mass

586.279

medical condition treated

stomach cancer, breast cancer, non-small-cell lung carcinoma, pancreatic cancer, colonic benign neoplasm, leukemia, rectum cancer, lymphoma, colon cancer, germ cell cancer, alveolar rhabdomyosarcoma, colon adenocarcinoma

pregnancy category

Australian pregnancy category D, US pregnancy category D

significant drug interaction

amiodarone, amprenavir, aprepitant, atazanavir, cimetidine, clarithromycin, darunavir, diltiazem, erythromycin, fluconazole, fosamprenavir, indinavir

subject has role

DNA polymerase inhibitors, topoisomerase inhibitor, phytogenic antineoplastic agents, radiosensitizer, topoisomerase I inhibitor, essential medicine

World Health Organisation international non-proprietary name

irinotecan