cimetidine

Details

Instance of

type of chemical entity

Subclass of

heterocyclic compound

Has parts

nitrogen, carbon

active ingredient in

Tagamet

canonical SMILES

CC1=C(N=CN1)CSCCNC(=NC)NC#N

chemical formula

C₁₀H₁₆N₆S

discoverer or inventor

John Colin Emmett

has use

medication

isomeric SMILES

CN/C(=N\CCSCC=1N=CNC1C)/NC#N

LiverTox likelihood score

LiverTox toxicity likelihood category B

mass

252.115716

medical condition treated

gastroesophageal reflux disease, peptic esophagitis, heartburn, gastric ulcer, indigestion, urticaria, duodenal ulcer, Zollinger–Ellison syndrome, peripheral vascular disease

physically interacts with

alcohol dehydrogenase (NAD), Histamine receptor H2, Solute carrier family 47 member 2, Solute carrier family 47 member 1, Solute carrier family 29 member 4

pregnancy category

Australian pregnancy category B1, US pregnancy category B

significant drug interaction

aminophylline, aminophylline, aminophylline, aminophylline, rac-warfarin, theophylline monohydrate, theophylline monohydrate, theophylline monohydrate, theophylline monohydrate, cyclosporine, cyclosporine, cyclosporine

subject has role

H2 antagonists, anti-ulcer drug, cytochrome P-450 CYP1A2 Inhibitors

World Health Organisation international non-proprietary name

cimetidine

Authority files