Gamma-aminobutyric acid type A receptor subunit beta2

Details

Instance of

protein

Subclass of

cysteine loop ligand-gated ion channel receptor

Part of

Neurotransmitter-gated ion-channel ligand-binding domain superfamily, Gamma-aminobutyric-acid A receptor, beta subunit, Neurotransmitter-gated ion-channel transmembrane domain superfamily, GABAA receptor, Neurotransmitter-gated ion-channel transmembrane domain, protein family, Neurotransmitter-gated ion-channel ligand-binding domain, protein family, Neurotransmitter-gated ion-channel, conserved site, protein family

Has parts

Neurotransmitter-gated ion-channel transmembrane domain, Neurotransmitter-gated ion-channel ligand-binding domain, Neurotransmitter-gated ion-channel, conserved site

biological process

gamma-aminobutyric acid signaling pathway, negative regulation of neuron apoptotic process, chemical synaptic transmission, cochlea development, regulation of neuron apoptotic process, neuron development, chloride transmembrane transport, synaptic transmission, GABAergic, hearing, ion transport, inner ear receptor cell development, chloride transport

cell component

integral component of membrane, cytosol, GABA-A receptor complex, postsynaptic membrane, membrane, plasma membrane, integral component of plasma membrane, synapse, chloride channel complex, cell junction, GABA receptor complex, extracellular exosome

encoded by

GABRB2

found in taxon

Homo sapiens

molecular function

inhibitory extracellular ligand-gated ion channel activity, ion channel activity, GABA receptor activity, chloride channel activity, extracellular ligand-gated ion channel activity, GABA-A receptor activity, transmembrane signaling receptor activity, extracellular ligand-gated ion channel activity, GABA receptor activity, transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential, GABA-gated chloride ion channel activity

physically interacts with

picrotoxin, metharbital, triclofos, butalbital, chlordiazepoxide, diazepam, prazepam, zopiclone, topiramate, clotiazepam, allopregnanolone, chlordiazepoxide hydrochloride