checkpoint kinase 2

Details

Instance of

protein

Part of

Protein kinase-like domain superfamily, SMAD/FHA domain superfamily, Forkhead-associated (FHA) domain, protein family, Protein kinase domain, protein family, Serine/threonine-protein kinase, active site, protein family

Has parts

forkhead-associated (FHA) domain, protein kinase domain, serine/threonine-protein kinase, active site

biological process

positive regulation of protein phosphorylation, regulation of transcription, DNA-templated, cellular response to bisphenol A, negative regulation of DNA damage checkpoint, phosphorylation, signal transduction in response to DNA damage, replicative senescence, DNA damage checkpoint signaling, protein stabilization, transcription, DNA-templated, cellular response to DNA damage stimulus, cell division

cell component

PML body, Golgi apparatus, nucleoplasm, telomere, nucleus, nucleus, cytoplasm

EC enzyme number

2.7.11.1

encoded by

CHEK2

found in taxon

Homo sapiens

molecular function

transferase activity, nucleotide binding, protein kinase activity, protein homodimerization activity, metal ion binding, protein serine/threonine kinase activity, protein binding, identical protein binding, protein kinase binding, ATP binding, ubiquitin protein ligase binding, kinase activity