topotecan

Details

Instance of

type of chemical entity

Subclass of

LSM-4296

Has parts

nitrogen, carbon

active ingredient in

Evotopin, Hycamtin, Potactasol, Topotecan Actavis, Topotecan Hospira, Topotecan Teva

canonical SMILES

CCC1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC(=C(C5=C4)CN(C)C)O)O

chemical formula

C₂₃H₂₃N₃O₅

has use

medication

isomeric SMILES

CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC(=C(C5=C4)CN(C)C)O)O

legal status (medicine)

boxed warning

manufacturer

Pfizer

mass

421.164

medical condition treated

lung oat cell carcinoma, lung benign neoplasm, ovarian cancer, non-small-cell lung carcinoma, bronchus carcinoma, neuroblastoma, susceptibility to, lung small cell carcinoma, ovarian carcinoma

pregnancy category

Australian pregnancy category D, US pregnancy category D

subject has role

topoisomerase inhibitor, topoisomerase I inhibitor

World Health Organisation international non-proprietary name

topotecan