dopamine beta-hydroxylase

Details

Instance of

protein

Part of

PHM/PNGase F domain superfamily, Copper type II, ascorbate-dependent monooxygenase, N-terminal domain superfamily, Tyramine beta-hydroxylase/Dopamine beta-hydroxylase, Copper type II, ascorbate-dependent monooxygenase-like, C-terminal, Copper type II, ascorbate-dependent monooxygenase, N-terminal domain, protein family, DOMON domain, protein family, Copper type II ascorbate-dependent monooxygenase, C-terminal domain, protein family, Copper type II, ascorbate-dependent monooxygenase, histidine-cluster-2 conserved site, protein family, Copper type II, ascorbate-dependent monooxygenase, histidine-cluster-1 conserved site, protein family

Has parts

Copper type II, ascorbate-dependent monooxygenase, histidine-cluster-2 conserved site, Copper type II ascorbate-dependent monooxygenase, C-terminal, Copper type II, ascorbate-dependent monooxygenase, N-terminal, DOMON domain, Copper type II, ascorbate-dependent monooxygenase, histidine-cluster-1 conserved site

biological process

response to amphetamine, chemical synaptic transmission, homoiothermy, leukocyte mediated immunity, visual learning, fear response, behavioral response to ethanol, locomotory behavior, regulation of extrinsic apoptotic signaling pathway, regulation of cell population proliferation, positive regulation of vasoconstriction, glucose homeostasis

cell component

cytoplasm, transport vesicle membrane, integral component of membrane, chromaffin granule lumen, chromaffin granule membrane, cytoplasmic vesicle, membrane, extracellular region, extracellular space, secretory granule membrane, secretory granule lumen, intracellular membrane-bounded organelle

EC enzyme number

1.14.17.1

encoded by

DBH

found in taxon

Homo sapiens

molecular function

metal ion binding, monooxygenase activity, oxidoreductase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen, L-ascorbic acid binding, catalytic activity, dopamine beta-monooxygenase activity, copper ion binding, dopamine beta-monooxygenase activity, copper ion binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen, dopamine beta-monooxygenase activity

physically interacts with

nepicastat