anakinra

pharmaceutical drug, interleukin 1 receptor antagonist

Details

Instance of: type of chemical entity
Subclass of: 7-[[2-(2-Amino-1,3-thiazol-4-yl)-2-(2,2-dimethylpropanoyloxymethoxyimino)acetyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Has parts: carbon
active ingredient in: Kineret
canonical SMILES: C=CC1=C(C(=O)O)N2C(=O)C(NC(=O)C(=NOCOC(=O)C(C)(C)C)c3csc(=N)[nH]3)C2SC1
chemical formula: C₂₀H₂₃N₅O₇S₂
defined daily dose: 0.1
has characteristic: biopharmaceutical
has use: medication
isomeric SMILES: C=CC1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)/C(=N\OCOC(=O)C(C)(C)C)c3csc(=N)[nH]3)C2SC1
LiverTox likelihood score: LiverTox toxicity likelihood category C
mass: 509.103890076
medical condition treated: rheumatoid arthritis, systemic-onset juvenile idiopathic arthritis, pericarditis
pregnancy category: Australian pregnancy category B1, US pregnancy category B
significant drug interaction: golimumab
subject has role: enzyme inhibitor

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