amphotericin B

Details

Instance of

type of chemical entity

Subclass of

amphotericin, APKFDSVGJQXUKY-ZCGADPMASA-N

canonical SMILES

CC1C=CC=CC=CC=CC=CC=CC=CC(CC2C(C(CC(O2)(CC(CC(C(CCC(CC(CC(=O)OC(C(C1O)C)C)O)O)O)O)O)O)O)C(=O)O)OC3C(C(C(C(O3)C)O)N)O

chemical formula

C₄₇H₇₃NO₁₇

defined daily dose

35, 0.2, 40, 0.4

found in taxon

Streptomyces hygroscopicus, Ralstonia solanacearum, Floricola striata, Streptomyces albolongus, Trichoderma brevicompactum, Toona ciliata, Colletotrichum higginsianum, Casearia sylvestris, Penicillium convolutum, Talaromyces convolutus, Aspergillus wentii, Streptomyces noursei

has use

medication, amebicide

isomeric SMILES

C[C@H]1/C=C/C=C/C=C/C=C/C=C/C=C/C=C/[C@@H](C[C@H]2[C@@H]([C@H](C[C@](O2)(C[C@H](C[C@H]([C@@H](CC[C@H](C[C@H](CC(=O)O[C@H]([C@@H]([C@@H]1O)C)C)O)O)O)O)O)O)O)C(=O)O)O[C@H]3[C@H]([C@H]([C@@H]([C@H](O3)C)O)N)O

LiverTox likelihood score

LiverTox toxicity likelihood category C

mass

923.488

medical condition treated

coccidioidomycosis, aspergillosis, fungal meningitis, chronic mucocutaneous candidiasis, cystitis, cryptococcosis, visceral leishmaniasis, neutropenia, peritonitis, paracoccidioidomycosis, blastomycosis, candidiasis

pregnancy category

US pregnancy category B

stereoisomer of

amphotericin B, amphotericin B, LSM-5443

subject has role

enzyme inhibitor, antibiotic, antifungal, antiprotozoal, WHO essential medicines, bactericide

World Health Organisation international non-proprietary name

amphotericin B

Authority files