Site-directed ligand discovery

Details

Instance of

scholarly article

Publication date

15 August 2000

author name string

D A Erlanson, A C Braisted, D R Raphael, M Randal, R M Stroud, E M Gordon, J A Wells

cites work

On the attribution and additivity of binding energies, Structure-based design of inhibitors specific for bacterial thymidylate synthase, The additivity of substrate fragments in enzyme–ligand binding, Structure, multiple site binding, and segmental accommodation in thymidylate synthase on binding dUMP and an anti-folate, Plastic adaptation toward mutations in proteins: structural comparison of thymidylate synthases, The CCP4 suite: programs for protein crystallography, The finer things in X-ray diffraction data collection, Improved methods for building protein models in electron density maps and the location of errors in these models, Structure-based discovery of inhibitors of thymidylate synthase, The catalytic mechanism and structure of thymidylate synthase, Preferential heterodimer formation by isolated leucine zippers from fos and jun, Discovering high-affinity ligands for proteins: SAR by NMR

issue

17

language of work or name

English

page(s)

9367-72

published in

Proceedings of the National Academy of Sciences of the United States of America

title

Site-directed ligand discovery

volume

97