LYN proto-oncogene, Src family tyrosine kinase

Details

Instance of

protein

Part of

SH3-like domain superfamily, Protein kinase-like domain superfamily, SH2 domain superfamily, Src family kinases (SFKs) [cytosol], Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family, Tyrosine-protein kinase Lyn, SH3 domain, protein family, SH2 domain, protein family, SH3 domain, protein family, Protein kinase domain, protein family, Protein kinase, ATP binding site, protein family, Tyrosine-protein kinase, catalytic domain, protein family, Tyrosine-protein kinase, active site, protein family

Has parts

tyrosine-protein kinase, active site, SH3 domain, protein kinase, ATP binding site, protein kinase domain, tyrosine-protein kinase, catalytic domain, SH2 domain, serine-threonine/tyrosine-protein kinase, catalytic domain, Tyrosine-protein kinase Lyn, SH2 domain, Tyrosine-protein kinase Lyn, SH3 domain

biological process

regulation of protein phosphorylation, cellular response to extracellular stimulus, cellular response to retinoic acid, positive regulation of B cell receptor signaling pathway, tolerance induction to self antigen, regulation of mast cell activation, regulation of cell adhesion mediated by integrin, cellular response to heat, response to amino acid, hemopoiesis, adaptive immune response, regulation of erythrocyte differentiation

cell component

cytoplasm, cytosol, membrane, extrinsic component of cytoplasmic side of plasma membrane, mitochondrial intermembrane space, perinuclear region of cytoplasm, nucleus, mitochondrial membranes, membrane raft, extracellular exosome, Golgi apparatus, plasma membrane

EC enzyme number

2.7.10.2

encoded by

LYN

found in taxon

Homo sapiens

molecular function

transmembrane transporter binding, SH3 domain binding, protein-containing complex binding, kinase activity, gamma-tubulin binding, signaling receptor binding, ATP binding, protein kinase activity, non-membrane spanning protein tyrosine kinase activity, enzyme binding, transferase activity, platelet-derived growth factor receptor binding

physically interacts with

bafetinib, bosutinib, SU6656