Glutamate ionotropic receptor NMDA type subunit 2B

Details

Instance of

protein

Part of

Periplasmic binding protein-like I, ionotropic glutamate receptor, metazoa, NMDA receptor, Receptor, ligand binding region, protein family, Ionotropic glutamate receptor domain, protein family, Glutamate [NMDA] receptor, epsilon subunit, C-terminal domain, protein family, Ionotropic glutamate receptor, L-glutamate and glycine-binding domain, protein family

Has parts

Ionotropic glutamate receptor, L-glutamate and glycine-binding domain, Glutamate [NMDA] receptor, epsilon subunit, C-terminal, Receptor, ligand binding region, Ionotropic glutamate receptor domain

biological process

glutamate receptor signaling pathway, ephrin receptor signaling pathway, ion transport, MAPK cascade, learning or memory, response to ethanol, chemical synaptic transmission, ionotropic glutamate receptor signaling pathway, excitatory postsynaptic potential, regulation of ion transmembrane transport, transport, calcium-mediated signaling

cell component

integral component of membrane, postsynaptic membrane, membrane, synapse, NMDA selective glutamate receptor complex, cell surface, cell junction, neuron projection, intracellular anatomical structure, integral component of plasma membrane, postsynaptic density, plasma membrane

encoded by

GRIN2B

found in taxon

Homo sapiens

molecular function

zinc ion binding, glycine binding, metal ion binding, ion channel activity, protein binding, ionotropic glutamate receptor activity, extracellularly glutamate-gated ion channel activity, NMDA glutamate receptor activity, glutamate binding, glutamate-gated calcium ion channel activity, amyloid-beta binding, NMDA glutamate receptor activity

physically interacts with

glycine, L-aspartic acid, homoquinolinic acid, Tetrazolylglycine, N-methyl-D-aspartic acid, 5,7-dichlorokynurenic acid, Midafotel, selfotel, amantadine, dizocilpine, (RS)-ketamine, phencyclidine