mitomycin

Details

Instance of

type of chemical entity

Subclass of

LSM-1590

Part of

mitomycin C metabolic process, mitomycin C catabolic process, mitomycin C biosynthetic process

active ingredient in

Mutamycin

canonical SMILES

CC1=C(C(=O)C2=C(C1=O)N3CC4C(C3(C2COC(=O)N)OC)N4)N

chemical formula

C₁₅H₁₈N₄O₅

different from

mitomycins

found in taxon

Streptomyces lavendulae, Streptomyces purpurascens, Streptomyces violaceus, Streptomyces, Streptomyces caespitosus

has use

medication

isomeric SMILES

CC1=C(C(=O)C2=C(C1=O)N3C[C@H]4[C@@H]([C@@]3([C@@H]2COC(=O)N)OC)N4)N

legal status (medicine)

boxed warning

mass

334.12772

medical condition treated

cribriform carcinoma, large intestine cancer, glaucoma, bladder cancer

pregnancy category

Australian pregnancy category D, US pregnancy category D

significant drug interaction

vinblastine, vinblastine

stereoisomer of

LSM-5621

subject has role

alkylating agent, DNA polymerase inhibitors, antineoplastic antibiotics, cross-linking reagent, carcinogen