valsartan

Details

Instance of

type of chemical entity

Subclass of

heterocyclic compound, carboxylic acid

Has parts

nitrogen, carbon

active ingredient in

Diovan

canonical SMILES

CCCCC(=O)N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NNN=N3)C(C(C)C)C(=O)O

chemical formula

C₂₄H₂₉N₅O₃

defined daily dose

80

has use

medication

isomeric SMILES

CCCCC(=O)N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NNN=N3)[C@@H](C(C)C)C(=O)O

legal status (medicine)

boxed warning

LiverTox likelihood score

LiverTox toxicity likelihood category D

mass

435.22704

medical condition treated

congestive heart failure, arterial hypertension, heart disease

physically interacts with

angiotensin II receptor type 1

pregnancy category

US pregnancy category D

significant drug interaction

lisinopril dihydrate, quinapril, ramipril, captopril, enalapril, trandolapril, fosinopril, perindopril, lisinopril dihydrate, quinapril, ramipril, captopril

significant event

Valsartan recall: global regulatory overview and future challenges, Diovan Incident

stereoisomer of

D-valsartan, N-(1-Oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-3-yl]methyl]-L-valine

subject has role

angiotensin II receptor antagonist, antihypertensive drug

World Health Organisation international non-proprietary name

valsartan